Anæstesi A-Z – ep. 5 | Postoperativ smertebehandling del 1

Fra flaskedreng til professor. Sådan lyder overskriften i Bramming ugeavis om denne episodes gæsteekspert og har du lyst, kan du læse mere om ham og hans karriere fra Brugsen i Bramming til Professor i Køge lige her.

Den unge 10 årige Ole, der startede som falskedreng i Brugsen er nu lidt ældre, professor i Køge og denne episodes ekspert. Og hvilken ekspert vi her har besøg af til emnet om postoperativ smertebehandling. Professor Ole Mathiesen har brugt sit anæstesilæge-liv på andre folks smerte. I klinikken, i forskningen og undervisningen. Han har sammen med Jørgen B. Dahl skrevet kapitlet om postoperativ smerte i anæstesibogen og i denne episode beriger han os med sin store viden om smertebehandling.

Under vores besøg på Oles kontor på Region Sjællands universitetshospital Køge faldt snakken så nemt, at tiden løb og indholdet voksede, så det er nu blevet til hele 3 episoder om emnet postoperativ smertebehandling.

I denne første episode bliver du klogere på hvad smerte er og smertefysiologi, hvordan vi måler den og hvad smerterne gør ved patienterne og deres morbiditet og mortalitet. VI åbner op for behandling af smerter og evidensen bag den multimodale smertebehandlingsstrategi.

Hvis du har behov for lige at få repeteret smertefysiologi kan vi varmt anbefale denne video:

For dig der vil dykke lidt dybere i litteraturen er det vigtigste udpluk af referencer til dagens episode at finde herunder i reference afsnittet.

Kh Sandra og Tobias

Referencer

Thybo KH, Hägi-Pedersen D, Dahl JB, Wetterslev J, Nersesjan M, Jakobsen JC, Pedersen NA, Overgaard S, Schrøder HM, Schmidt H, Bjørck JG, Skovmand K, Frederiksen R, Buus-Nielsen M, Sørensen CV, Kruuse LS, Lindholm P, Mathiesen O. Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial. JAMA. 2019 Feb 12;321(6):562-571. PMID 30747964

Schwenk ES, Viscusi ER, Buvanendran A, Hurley RW, Wasan AD, Narouze S, Bhatia A, Davis FN, Hooten WM, Cohen SP. Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. Reg Anesth Pain Med. 2018 Jul;43(5):456-466. PMID 29870457

Fabritius ML, Wetterslev J, Mathiesen O, Dahl JB. Dose-related beneficial and harmful effects of gabapentin in postoperative pain management – post hoc analyses from a systematic review with meta-analyses and trial sequential analyses. J Pain Res. 2017 Nov 1;10:2547-2563. PMID 29138592

Fabritius ML, Strøm C, Koyuncu S, Jæger P, Petersen PL, Geisler A, Wetterslev J, Dahl JB, Mathiesen O. Benefit and harm of pregabalin in acute pain treatment: a systematic review with meta-analyses and trial sequential analyses. Br J Anaesth. 2017 Oct 1;119(4):775-791. PMID 29121288

Fabritius ML, Geisler A, Petersen PL, Nikolajsen L, Hansen MS, Kontinen V, Hamunen K, Dahl JB, Wetterslev J, Mathiesen O. Gabapentin for post-operative pain management – a systematic review with meta-analyses and trial sequential analyses. Acta Anaesthesiol Scand. 2016 Oct;60(9):1188-208. doi: 10.1111/aas.12766. Epub 2016 Jul 18. PMID 27426431

Dahl JB, Nielsen RV, Wetterslev J, Nikolajsen L, Hamunen K, Kontinen VK, Hansen MS, Kjer JJ, Mathiesen O; Scandinavian Postoperative Pain Alliance (ScaPAlli). Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review. Acta Anaesthesiol Scand. 2014 Nov;58(10):1165-81. PMID 25124340

Mathiesen O, Wetterslev J, Kontinen VK, Pommergaard HC, Nikolajsen L, Rosenberg J, Hansen MS, Hamunen K, Kjer JJ, Dahl JB; Scandinavian Postoperative Pain Alliance (ScaPAlli). Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review. Acta Anaesthesiol Scand. 2014 Nov;58(10):1182-98. PMID 25116762

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Sandra Viggers
Star skater, simulationista by day , anaesthesia by night and #meded choreographer. Coming to a SIM room near you. With a shark.
Sandra Viggers on LinkedinSandra Viggers on Twitter
Tobias Sonne
MD, currently finalising his specialist registrar training in anesthesiology. Moonlights as SAR medical doctor and co-host at ‘Anæstesi A - Z’.
Tobias Sonne on Twitter

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Inspiring article. I admire the valuable information you offer in your articles.

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